WHAT: Doug Lund DNA Day
HOSTED BY: UNK Department of Biology
TITLE: “Redefining mouse transgenesis with CRISPR-Cas9 technology”
TOPIC: The CRISPR-Cas9 tool has radically changed the way traditional transgenic technologies are practiced. The University of Nebraska Medical Center has pioneered some breakthrough technologies using the CRISPR approach to create complex animal models, including long cassette knock-ins and conditional knockout mouse models. These technological contributions, particularly Easi (Efficient additions with ssDNA inserts)-CRISPR and genome editing via oviductal nucleic acids delivery, have been widely adapted in the animal transgenesis field.
PRESENTER: Channabasavaiah Gurumurthy is a professor of pharmacology and experimental neuroscience at UNMC and director of the Mouse Genome Engineering Core Facility. He develops genome editing technologies and custom mouse models useful to research ranging from cancer to COVID-19. Easi-CRISPR and i-GONAD, the two popular technologies he co-developed along with his long-term collaborator Masato Ohtsuka, are now regarded as revolutionary methods in the mouse genome engineering field. Gurumurthy is one of six researchers who received the National Human Genome Research Institute’s inaugural Genomic Innovator Award.
TIME: 4 p.m.
DATE: Friday, April 30
ABOUT DNA DAY: DNA Day was established in 2013 in honor of Doug Lund, a longtime UNK biology professor who encouraged scientific inquiry and a love for biology in all his students.