KEARNEY – Harvard immunologist, Dr. Jon Kagan, will give two presentations at the University of Nebraska at Kearney Friday (Nov. 7). The seminar and Science Café are sponsored by Sigma Xi, the Scientific Research Society.
Who: Jon Kagan, Department of Pediatrics, Harvard Medical School
What: “Initiation and Regulation of Innate Immunity”
When: 2:30 p.m.
Where: Bruner Hall of Science room 269
What: Science Café – “Vaccines: How they work and why you should care”
When: 5 p.m.
Where: The Loft at Cunningham’s Journal, 15 W. 23rd St.
About Dr. Jon Kagan: Kagan studies Pattern Recognition Receptor signaling pathways as a means of understanding the earliest events that initiate immunity to infection. His work began with studies of the Toll-like Receptor (TLR) signaling networks, which mainly operate in professional phagocytes and function to detect microorganisms that enter our bodies. His research has focused primarily on defining the subcellular site of TLR signal transduction. He has established that TLR adaptor proteins function as pairs of sorting and signaling adaptors, where the sorting adaptor functions to recruit the signaling adaptor to a subcellular site that contains an activated TLR. His work provided the first in vivo evidence that the localization of these adaptor proteins is important for controlling microbial infections.